1726, Jonathan Swift, Gulliver's Travels, Oxford University Press, 2006, A Voyage to the Country of the Houyhnhnms, Chapter VI, p. 236,
Or else from the same Store-house, with some other poysonous Additions, they command us to take in at the Orifice above or below, (just as the Physician then happens to be disposed) a Medicine equally annoying and disgustful to the Bowels; which relaxing the Belly, drives down all before it: And this they call a Purge, or a Clyster.