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Definition of "labile" in English

adjective

  1. Liable to slip, err, fall, or apostatize.

  2. Apt or likely to change.

  3. (chemistry, of a compound or bond) Kinetically unstable; rapidly cleaved (and possibly reformed).

    • Certain drugs can be conjugated to polymer molecules with a linkage that is labile at low pH to effect controlled release in a cellular endosome.
    • Water ligands typically bind metals in a labile fashion and are rapidly interchanged in aqueous solution.
  4. (linguistics, of a verb) Able to change valency without changing its form; especially, able to be used both transitively and intransitively without changing its form.