Definition of "refractory" in English

adjective

1. Obstinate and unruly; strongly opposed to something.

2. Not affected by great heat.

3. (medicine) Resistant to treatment; not responding adequately to therapy.

4. (biology) Incapable of registering a reaction or stimulus.

noun

1. A material or piece of material, such as a brick, that has a very high melting point.

2. A plant or factory that produces such material.