noun
A high point: the highest point of any range, the most developed stage of any process, or the culmination of any field or historical period.
A paragon: a person or thing representing such a high point.
(rare) Full bloom or reproductive maturity.
(euphemistic) Sexual orgasm.
(medicine) Synonym of crisis, the decisive moment in the course of an illness.
Alternative letter-case form of Acme, particularly as a threading format.