(rare, often medicine) The state or characteristic of having dulled senses or limited awareness.
[T]here are beings [who] . . . revel, with a lively zest, among all the things that are most foul and loathsome. . . . Sensuality, force of temper, inertness, obtundity of perception, personal idolatry, and the destitution of the higher and better emotions of humanity, are the ingredients of a constitution of this order.