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Researchers at The Scripps Research Institute in La Jolla, California, modified vancomycin, invented 60 years ago and considered a last-resort treatment against many of these infections. They made a key change to its molecular structure, interfering with how the bacterium, enterococcus, makes protective cell walls.
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The modification is in addition to two previous changes made by the Scripps team that improved the drug’s potency, so less of it is needed to treat an infection.
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